Malaria Free Game Reserves

South Africa has a wonderful range of malaria-free game reserves throughout the country. Enjoy an authentic safari experience with complete peace of mind at these exceptional properties.

For complete peace of mind on your safari holiday especially if travelling with young children, South Africa has a number of excellent malaria-free game reserves.

The reserves we feature have been handpicked for their quality of gameviewing, range of safari activities and outstanding accommodation options. They also cater for children, with exclusive-use lodges and in many cases, fantastic kids’ programs.

South Africa’s fifth-largest game reserve, Madikwe is located on the border of Botswana on the fringes of the Kalahari Desert. Once overgrazed farmland, the landscape is now home to 66 mammal species including all of the must-see “Big 5”: elephant, rhino, buffalo, lion and leopard. There are also packs of rare wild dog on this 185,000 acre reserve, which is accessible only to guests staying at safari lodges and camps within its boundaries.

On the Northern Cape near the country’s border with Botswana lies South Africa’s largest private game reserve. Tswalu Kalahari comprises of 272,000 acres traversed by a maximum of ten gameviewing vehicles at any given time, ensuring incredible exclusivity. Track endangered desert rhinos and look for comical meerkats amid breathtakingly vast landscapes of open grassland and rolling dunes.

The country’s Eastern Cape is home to some enchantingly beautiful ecosystems, ranging from semi-arid Karoo desert to rugged hills. Kwandwe and Shamwari are two outstanding private game reserves in this area, offering a wide range of activities to uncover resident big game as well as eye-opening insights into the challenges facing wildlife conservationists in South Africa.


Malaria Free Game Reserves Highlights

  • Safari destinations ideal for families with young children
  • Rich in big game and rare animals such as wild dog and cheetah
  • Diverse landscapes from desert to dramatic hills
  • Lodges which offer outstanding kids’ programs so adults can relax
  • Support conservation and take part in animal conservation projects

When To Go

Excellent all year round, with game easiest to observe during the dry season (May-Sep). Birding is however, best in the green, wet season (Oct-Apr). Being family-orientated destinations, these reserves are busiest during South African school holidays, especially around December.


Accommodation in malaria-free game reserves.

South Africa has a wonderful range of malaria-free game reserves throughout the country – an important consideration for travellers with young children and for those who have existing health problems. Enjoy an authentic safari experience with complete peace of mind at these properties. For information on additional accommodation not featured, please contact us.

Kwandwe Private Game Reserve

Malaria-free Kwandwe Private Game Reserve on South Africa’s Eastern Cape offers five safari lodges, each designed to showcase the remote beauty of the surrounding landscape.

Madikwe River Lodge

Family-friendly Madikwe River Lodge is a relaxed, comfortable safari lodge set in South Africa's wonderful, malaria-free Madikwe Game Reserve which is home to all of the iconic "Big 5" and much more.

Shamwari Game Reserve

On South Africa’s pristine Eastern Cape, Shamwari Game Reserve is an excellent safari destination being malaria-free and home to fantastic wildlife including all of the legendary "Big 5".

Tau Game Lodge

Located on the malaria-free Madikwe Game Reserve, Tau Game Lodge offers an authentic safari experience in a relaxed, family-friendly atmosphere.

Tswalu Kalahari

South Africa’s largest private game reserve, Tswalu Kalahari is inhabited by over 80 mammal species including meerkat and desert rhino.

Tuningi Safari Lodge

On the vast Madikwe Game Reserve is the luxurious Tuningi Safari Lodge as well as family-friendly Little Tuningi, a self-contained private villa.


South Africa Itineraries

The following itineraries are just some of the many experiences that we can design for you. All of our tours are private, independent and tailor-made to your personal travelling requirements. Please contact us to begin customising your personalised South Africa experience.

No grid was found for: south-africa-itinerary-2.

Find out more about our tailor made African safaris.
Get in touch with one of our Destination Specialists.

Find out more about our tailor made African safaris

More of South Africa



Sign up to receive updates about exciting journeys, special offers and more